<title>X-ray crystallography with microfocus x-ray sources</title>

Abstract

For X-ray structure determination of biological macromolecular crystals interest has shifted to the use of very small crystals (less than 0.01 mm in diameter) with relatively large mosaic spreads (up to 10^-2 radians). For this purpose we are investigating mono-capillary optics and planar-parabolic and planar-elliptical mirrors. For studies of this type a low-power microfocus source with appropriate optics can compete favorably with high-power rotating-anode x-ray generators.