Bioadhesive Drug Delivery Systems

Abstract

Fundamentals of Bioadhesion Definitions, Mechanisms, and Theories of Bioadhesion Donald E. Chickering III and Edith Mathiowitz The Role of Water Movement and Polymer Hydration in Mucoadhesion John D. Smart A Rheological Approach to Explain the Mucoadhesive Behavior of Polymer Hydrogels Carla Marcella Caramella, Silvia Rossi, and Maria Cristina Bonferoni Functional Histology of Epithelia Relevant for Drug Delivery: Respiratory Tract, Digestive Tract, Eye, Skin, and Vagina Udo Schumacher and Dietlind Schumacher Biochemical and Functional Aspects of Mucus and Mucin-Type Glycoproteins Barry James Campbell Methods of Evaluating Bioadhesive Interactions Adaptation of a Microbalance to Measure Bioadhesive Properties of Microspheres Donald E. Chickering III, Camilla A. Santos, and Edith Mathiowitz Novel Magnetic Technique to Measure Bioadhesion Benjamin A. Hertzog and Edith Mathiowitz Principles of Skin Adhesion and Methods for Measuring Adhesion of Transdermal Systems Michael Horstmann, Walter Muller, and Bodo Asmussen Force Microscopy of Cells to Measure Bioadhesion E. zur Muhlen, P. Koschinski, S. Gehring, Robert Ros, Louis Tiefenhauer, Eleonore Haltner, Claus-Michael Lehr, Uwe Hartmann, Falk Schwesinger, and A. Pluckthun Direct Measurement of Molecular-Level Forces and Adhesion in Biological Systems James Schneider and Matthew Tirrell A Centrifugation Method for Measurement of Two-Dimensional Binding Characteristics of Receptor-Ligand Interaction Cheng Zhu, James W. Piper, and Robert A. Swerlick Novel Concepts and Strategies for Bioadhesive Drug Delivery Systems Multifunctional Polymers for the Peroral Delivery of Peptide Drugs Henrik L. Luessen, J. Coos Verhoef, A. (Bert) G. de Boer, H. E. Junginger, Bas J. de Leeuw, Gerrit Borchard, and Claus-Michael Lehr Chitosan and Chitosan Derivatives as Absorption Enhancers for Peptide Drugs Across Mucosal Epithelia A. F. Kotze, Henrik L. Luessen, M. Thanou, J. Coos Verhoef, A. (Bert) G. de Boer, H. E. Junginger, and Claus-Michael Lehr Plant Lectins for Oral Drug Delivery to Different Parts of the Gastrointestinal Tract Arpad Pusztai, Susan Bardocz, and Stanley W. B. Ewen Bacterial Invasion Factors and Lectins as Second-Generation Bioadhesives James H. Easson, Eleonore Haltner, Claus-Michael Lehr, and Dieter Jahn Novel PEG-Containing Acrylate Copolymers with Improved Mucoadhesive Properties Amir H. Shojaei and Xiaoling Li Bioadhesive, Bioerodible Polymers for Increased Intestinal Uptake Gerardo P. Carino, Jules S. Jacob, C. James Chen, Camilla A. Santos, Benjamin A. Hertzog, and Edith Mathiowitz Development Issues of Bioadhesive Drug Delivery Systems: Products and Clinical Trials Novel Formulation Approaches to Oral Mucoadhesive Drug Delivery Systems Yohko Akiyama and Naoki Nagahara Bioadhesive Formulations for Nasal Peptide Delivery Lisbeth Illum Development of Bioadhesive Buccal Patches Jian-Hwa Guo and Karsten Cremer Vaginal Delivery of Calcitonin by Hyaluronic Acid Formulations Julie L. Richardson and Trevor I. Armstrong Ocular Bioadhesive Drug Delivery Systems Marco Fabrizio Saettone, Susi Burgalassi, and Patrizia Chetoni Bioadhesive Preparations as Topical Dosage Forms Yoshiharu Machida and Tsuneji Nagai