JOURNAL ARTICLE
SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity
Dawid LewandowskiPiotr RuszkowskiAnita PińskaGrzegorz SchroederJoanna Kurczewska
Year: 2015 Journal: PLoS ONE Vol: 10 (7)Pages: e0132541-e0132541 Publisher: Public Library of Science
Abstract
Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg mL(-1)).
Keywords:
HeLa Mesoporous silica Gallic acid Cytotoxic T cell Chemistry Conjugated system Mesoporous material Covalent bond Nuclear chemistry Combinatorial chemistry Biochemistry Organic chemistry Cell Polymer In vitro Catalysis
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12
Cited By
0.00
FWCI (Field Weighted Citation Impact)
31
Refs
0.02
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Citation History
Topics
Mesoporous Materials and Catalysis
Physical Sciences → Materials Science → Materials Chemistry
Natural product bioactivities and synthesis
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Tannin, Tannase and Anticancer Activities
Life Sciences → Immunology and Microbiology → Applied Microbiology and Biotechnology
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