Muscle tissue regeneration

Abstract

Abstract: Muscle is unique among tissues because it generates its own force, presenting a unique challenge in tissue engineering. new tissue developed from the scaffold must not only have structural integrity, it must also be able to coordinate the protein-based changes necessary for contraction and force generation. in this chapter we will investigate the tissue engineering of muscle, specifically the use of electrospun nanofibres in skeletal muscle tissue engineering. We will focus on the advantages of nanofibrous matrices for muscle regeneration and how investigators combine nanofibres with different types of external stimulation to enhance tissue growth.