Infrared evanescent wave bio-sensors

Abstract

Original tapered infrared chalcogenide glass fibers have been developed in order to analyse by evanescent wave absorption the IR signatures of biomolecules in the 2 to 12 /spl mu/m range. In using a small contact between the fiber and the analytes, in situ measurements have been performed on biofilms, serum, liver and lung cells allowing the detection of metabolic anomalies.